Lunesta (eszopiclone) will stay within a person’s system for approximately 24 to 48 hours. The half-life of this drug is six hours. A half-life means that after six hours of taking the medication, only half the dose of Lunesta pill remains in a person’s system. Doctors typically prescribe Lunesta medication for the treatment of sleep disorders like insomnia. Generic Lunesta is a sedative-hypnotic drug, and it acts on the brain to produce calming effects. Prescribed for up to two weeks only, the dosage of Lunesta sleeping pill rarely exceeds 3 mg a night as a solution for sleep problems. However, even 3 mg Lunesta will take at least 24 to 48 hours to cycle out of the body completely. In general, Lunesta does not accumulate in the system from a once-daily intake. However, overall health and age can affect how long the body processes and rids itself of Lunesta.
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