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Gabapentin is a prescription medication used to treat various conditions including epilepsy/seizures, neuropathic pain, restless legs syndrome, and hot flashes associated with menopause. Here are the details about gabapentin:
Mechanism of action: While the exact mechanism of action is not fully understood, gabapentin is believed to work by binding to certain calcium channels in the brain, reducing the release of certain neurotransmitters, and modulating the activity of excitatory neurons.
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Approved uses:
Epilepsy/Seizures: Gabapentin is used as an adjunctive therapy for the treatment of partial seizures and the management of postherpetic neuralgia (nerve pain caused by herpes zoster).
Neuropathic Pain: Gabapentin is approved for the treatment of diabetic peripheral neuropathy and postherpetic neuralgia.
Restless Legs Syndrome: Gabapentin enacarbil, a prodrug of gabapentin, is approved for the treatment of moderate to severe primary restless legs syndrome.
Hot Flashes: Gabapentin can also be used "off-label" to help reduce hot flashes in menopausal women.
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