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Ambien is primarily used to treat insomnia, a sleep disorder characterized by difficulty falling asleep, staying asleep, or both. Ambien is intended for short-term use, usually for no longer than a few weeks. Prolonged or continuous use can lead to tolerance (requiring higher doses for the same effect) and dependence. Zolpidem works by enhancing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits brain activity. This action helps calm the brain and promote sleep. Immediate-release Ambien typically helps users fall asleep quickly, while extended-release Ambien CR is designed to help individuals stay asleep throughout the night. The duration of action depends on the formulation.

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