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Butalbital: Butalbital is a barbiturate, a class of drugs that depress the central nervous system. Its mechanism of action involves binding to GABA-A receptors, facilitating inhibitory neurotransmission. This results in a generalized calming effect on the central nervous system, helping to alleviate tension and reduce headache symptoms. However, it's important to note that barbiturates, including butalbital, have the potential for abuse and dependence.

Acetaminophen: Acetaminophen is a widely used analgesic (pain reliever) and antipyretic (fever reducer). It works by inhibiting the synthesis of prostaglandins in the central nervous system, which are substances that sensitize pain receptors and contribute to fever. Acetaminophen is effective in reducing pain and fever but lacks the anti-inflammatory properties of nonsteroidal anti-inflammatory drugs (NSAIDs).